Familial polyposis is a rare hereditary disease of the colon and rectum. Because it has serious complications, early recognition and proper management are important. This disease is charact-erized by large number of adenomatous polyps arising through the mucosa of the colon and rectum. It dose not involve the small intestine.
At present, all are agreed that surgical removal of the colon is indicated, but the proper fate of the terminal bowel segment, rectum, has become the subject of heated debate.
We experienced one case of innummerable adenomatous polyps in the rectum and colon, com-bined with rectal adenocarcinoma in 34 years old male. The polyps were estimated more than 3, 000 in number and were varied in their size.
On admission, chief complaints were bloody stool, perianal pain and weight loss of 6 months duration. Furthermore, he has been suffered from bowel habit changes and defecation difficulty for about 10 years.
He underwent total colectomy and permanent ileostomy by two stage procedures because of mis-diagnosis of polyposis on admission.
This case is considered familial polyposis by a new mutation, because a positive family history cannot be elicited in his past generation and his own generation. Inheritance, however, might be obtained by means of family survey for long-time in his next generation.
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